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PHR1216

Supelco

癸二酸二丁酯

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
癸二酸二正丁酯, 皮脂酸二丁酯
线性分子式:
[-(CH2)4CO2(CH2)3CH3]2
CAS号:
109-43-3
分子量:
314.46
Beilstein:
1798308
EC 号:
203-672-5
MDL编号:
MFCD00027218
PubChem化学物质编号:
329823223
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1187091

API类

dibutyl sebacate

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.441 (lit.)

bp

178-179 °C/3 mmHg (lit.)

密度

0.936 g/mL at 25 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

CCCCOC(=O)CCCCCCCCC(=O)OCCCC

InChI

1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3

InChI key

PYGXAGIECVVIOZ-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA9029 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

366.8 °F - open cup

闪点(°C)

186 °C - open cup

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索取COA

Burdock AG et al.
Encyclopedia of Food & Color Additives, 1 (1997)
Thomas Quinten et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71(1), 145-154 (2008-05-31)
The aim of this study was to develop sustained-release matrix tablets by means of injection moulding and to evaluate the influence of process temperature, matrix composition (EC and HPMC concentration) and viscosity grade of ethylcellulose (EC) and hydroxypropylmethylcellulose (HPMC) on
I J Hardy et al.
International journal of pharmaceutics, 311(1-2), 26-32 (2006-01-25)
The compression and compaction properties of plasticised high molecular weight USP2208 HPMC were investigated with the aim of improving tablet formation in HPMC matrices. Experiments were conducted on binary polymer-plasticiser mixtures containing 17 wt.% plasticiser, and on a model hydrophilic
T Bussemer et al.
Drug development and industrial pharmacy, 29(6), 623-630 (2003-08-02)
The mechanical properties of polymer films used in pharmaceutical coatings of pulsatile drug delivery systems were evaluated in the dry and the wet state by a newly developed puncture test, which allowed the time-dependent measurement of the mechanical properties on
A Wyss et al.
Biotechnology and bioengineering, 87(6), 734-742 (2004-08-27)
A novel perstraction system using liquid-core microcapsules for pesticide and herbicide removal from aqueous environments is proposed. The microcapsules contain an oil, dibutyl sebacate, surrounded by a hydrogel membrane. The extraction efficiency of the capsules was demonstrated with atrazine, methylparathion
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