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Merck
CN

PHR1248

麦芽糖醇

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-O-α-吡喃葡萄糖基- D -山梨醇

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关于此项目

经验公式(希尔记法):
C12H24O11
化学文摘社编号:
分子量:
344.31
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
209-567-0
Beilstein/REAXYS Number:
89983
MDL number:
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产品名称

麦芽糖醇, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

VQHSOMBJVWLPSR-WUJBLJFYSA-N

InChI

1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1

SMILES string

OC[C@H](O)[C@@H](O)[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)CO

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. M0160000
traceable to USP 1374907

API family

maltitol

CofA

current certificate can be downloaded

analyte chemical class(es)

oligosaccharides

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

149-152 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Biochem/physiol Actions

具有弱遗传毒性作用的糖替代品。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Maltitol is a sugar alcohol and nutritive sweetener, exhibiting reduced laxative effects, hence finds applications in different food products, beverages and dietary supplements.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7670 in the slot below. This is an example certificate only and may not be the lot that you receive.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
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分析证书(COA)

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Determination of maltitol, isomaltitol, and lactitol by high-pH anion-exchange chromatography with pulsed amperometric detection
Cataldi.I.RT, et al.
Journal of Agricultural and Food Chemistry, 47(1), 157-163 (1999)
Simultaneous separation and determination of erythritol, xylitol, sorbitol, mannitol, maltitol, fructose, glucose, sucrose and maltose in food products by high performance liquid chromatography coupled to charged aerosol detector
Grembecka M, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 117, 77-82 (2014)
A Secchi et al.
Klinische Wochenschrift, 64(6), 265-269 (1986-03-17)
The present study was aimed to investigate the metabolic effects of acute and chronic oral administration of maltitol (4-O-i-D-glucopyranosyl-D-glucitol), a hypocaloric sweetener obtained from maltose by catalytic hydrogenation. Fifty grams of maltitol induced a increase lower glycemic and insulinemic than
Emma Beards et al.
The British journal of nutrition, 104(5), 701-708 (2010-04-08)
Sweeteners are being sourced to lower the energetic value of confectionery including chocolates. Some, especially non-digestible carbohydrates, may possess other benefits for human health upon their fermentation by the colonic microbiota. The present study assessed non-digestible carbohydrate sweeteners, selected for
Ana Rodriguez-Mateos et al.
The British journal of nutrition, 108(12), 2243-2250 (2012-03-09)
The beneficial effects of cocoa on vascular function are mediated by the absorption of monomeric flavanols into the circulation from the small intestine. As such, an understanding of the impact of the food matrix on the delivery of flavanols to

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