PHR1677
地蒽酚
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
地蒽酚, 1,8,9-蒽三酚, 1,8-二羟基蒽-9(10H)-酮, 二羟蒽酚, 蒽林
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关于此项目
经验公式（希尔记法）:
C14H10O3
化学文摘社编号:
分子量:
226.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-538-0
Beilstein/REAXYS Number:
2054360
MDL number:
InChI key
NUZWLKWWNNJHPT-UHFFFAOYSA-N
InChI
1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
SMILES string
Oc1cccc2Cc3cccc(O)c3C(=O)c12
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. D2953000, traceable to USP 1039006
API family
anthralin, dithranol
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
178-181 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
General description
Anthralin (Dithranol) is the synthetic form of chrysarobin. It is widely used as a medication for the human skin affected with psoriasis and in short contact therapy to minimize the staining, irritation, etc.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Anthralin (Dithranol) may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high pressure liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6122 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Psoriasis and Psoriatic Arthritis: An Integrated Approach, 70(11), 1205-1207 (2005)
High-pressure liquid chromatographic determination of anthralin in ointments
Caron C-J, et al.
Journal of Pharmaceutical Sciences, 70(11), 1205-1207 (1981)
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