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Merck
CN

PHR1677

地蒽酚

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

地蒽酚, 1,8,9-蒽三酚, 1,8-二羟基蒽-9(10H)-酮, 二羟蒽酚, 蒽林

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经验公式（希尔记法）:
C14H10O3
化学文摘社编号:
1143-38-0
分子量:
226.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823549
EC Number:
214-538-0
Beilstein/REAXYS Number:
2054360
MDL number:
MFCD00053409

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产品名称

地蒽酚, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

NUZWLKWWNNJHPT-UHFFFAOYSA-N

InChI

1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2

SMILES string

Oc1cccc2Cc3cccc(O)c3C(=O)c12

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. D2953000
traceable to USP 1039006

API family

anthralin, dithranol

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

178-181 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Anthralin (Dithranol) may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high pressure liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Anthralin (Dithranol) is the synthetic form of chrysarobin. It is widely used as a medication for the human skin affected with psoriasis and in short contact therapy to minimize the staining, irritation, etc.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6122 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

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Psoriasis and Psoriatic Arthritis: An Integrated Approach, 70(11), 1205-1207 (2005)
High-pressure liquid chromatographic determination of anthralin in ointments
Caron C-J, et al.
Journal of Pharmaceutical Sciences, 70(11), 1205-1207 (1981)

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