PHR1705
盐酸甲氟喹
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
甲氟喹 盐酸盐, (AS)-rel-a-(2R)-2-哌啶基-2,8-双(三氟甲基)-4-喹啉甲醇单盐酸盐
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关于此项目
经验公式（希尔记法）:
C17H17ClF6N2O
化学文摘社编号:
分子量:
414.77
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
257-412-0
MDL number:
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. M0253000, traceable to USP 1379059
API family
mefloquine
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
Cl[H].[H][C@@]1(CCCCN1)[C@@H](O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F
InChI
1S/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/m1./s1
InChI key
WESWYMRNZNDGBX-YLCXCWDSSA-N
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Application
Mefloquine Hydrochloride may be used as a pharmaceutical reference standard for the determination of mefloquine in pharmaceutical formulations and plasma samples by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
间隙连接通道Cx36和Cx50的阻断剂。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3945 in the slot below. This is an example certificate only and may not be the lot that you receive.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Development of a generic micellar electrokinetic chromatography method for the separation of 15 antimalarial drugs as a tool to detect medicine counterfeiting.
Lamalle C, et al.
Electrophoresis, 33(11), 1669-1678 (2012)
Screening study of SFC critical method parameters for the determination of pharmaceutical compounds.
Dispas A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 125(31), 339-354 (2016)
Development and validation of a reversed-phase LC method for analysing potentially counterfeit antimalarial medicines.
Gaudiano MC, et al.
Journal of Pharmaceutical and Biomedical Analysis, 42(1), 132-135 (2006)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1705-1G | 04061834801849 |