PHR2063
盐酸氨溴索
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
盐酸氨溴索 盐酸盐, 2-氨基-3,5-二溴-N-（ 反式 -4-羟基环己基）苄胺
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关于此项目
经验公式（希尔记法）:
C13H18Br2N2O · HCl
化学文摘社编号:
分子量:
414.56
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. A0363700
API类
ambroxol
CofA
current certificate can be downloaded
应用
pharmaceutical small molecule
包装形式
neat
储存温度
2-8°C
SMILES字符串
Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
InChI
1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
InChI key
QNVKOSLOVOTXKF-PFWPSKEQSA-N
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相关类别
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ambroxol hydrochloride is a mucolytic expectorant. It is a metabolite of bromhexine. It stimulates the transportation of viscous secretions in the respiratory organs and reduces the accumulation of the secretions.
应用
Ambroxol Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical dosage forms by high performance liquid chromatography and sequential injection chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB8553 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column
Satinsky D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(2), 287-293 (2006)
Sequential injection chromatographic determination of ambroxol hydrochloride and doxycycline in pharmaceutical preparations.
Satinsky D, et al.
Talanta, 68(2), 214-218 (2005)
Quantitative determination of levofloxacin and ambroxol hydrochloride in pharmaceutical dosage form by reversed-phase high performance liquid chromatography.
Kothekar M K, et al.
Eurasian Journal of Analytical Chemistry, 2(1), 21-31 (2007)
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