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Merck
CN

PHR3029

洛莫司汀

pharmaceutical secondary standard, certified reference material

别名:

Lomustine, 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

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关于此项目

经验公式(希尔记法):
C9H16ClN3O2
化学文摘社编号:
分子量:
233.70
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1369419

API family

lomustine

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

application(s)

pharmaceutical

storage temp.

2-8°C

SMILES string

ClCCN(N=O)C(=O)NC1CCCCC1

InChI

1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)

InChI key

GQYIWUVLTXOXAJ-UHFFFAOYSA-N

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Lomustine can be used in quantitative determination of analyte in rat plasma using HPLC/UV) method. It can also be used as a reference standard in the determination of lomustine capsules.

Biochem/physiol Actions

Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
PHR3029-500MG04065266899542