产品名称
二丙酸倍氯米松, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
SMILES string
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C
InChI key
KUVIULQEHSCUHY-XYWKZLDCSA-N
grade
pharmaceutical primary standard
API family
beclometasone
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... NR3C1(2908)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Beclomethasone dipropionate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Beclomethasone Dipropionate Compounded Oral Solution
- Betamethasone Dipropionate
- Betamethasone Dipropionate Cream
- Betamethasone Dipropionate Lotion
- Betamethasone Dipropionate Ointment
- Betamethasone Valerate
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2
target_organs
Adrenal gland,Immune system,Bone
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
J C Guérin et al.
Presse medicale (Paris, France : 1983), 21(32), 1526-1531 (1992-10-03)
Beclomethasone dipropionate has now been used for more than 10 years during which our knowledge of how to use inhaled corticosteroids has gradually improved: high dose initial treatment followed by progressive reduction down to the minimum effective dosage; administration in
Effect of inhaled beclomethasone dipropionate and budesonide on adrenal function, skin changes and cataract formation.
R G Dluhy
Respiratory medicine, 92 Suppl B, 15-23 (1999-04-08)
T B Edwards
Clinical therapeutics, 17(6), 1032-1041 (1995-11-01)
There is an increasing trend toward topical intranasal corticosteroids as the preferred treatment for seasonal or perennial allergic rhinitis. This trend is based on the fact that the chronic, mucosal inflammation that accompanies allergic rhinitis responds to anti-inflammatory drugs such
Effect of inhaled beclomethasone dipropionate and budesonide on growth in children with asthma.
D B Allen
Respiratory medicine, 92 Suppl B, 37-45 (1999-04-08)
George B McDonald
Expert opinion on investigational drugs, 16(10), 1709-1724 (2007-10-10)
Beclomethasone dipropionate (BDP) is a topically active anti-inflammatory corticosteroid. Oral BDP is metabolized in the intestine to a potent metabolite, 17-beclomethasone monopropionate (17-BMP). An oral formulation (orBec; DOR BioPharma), consisting of a gastric release and an enteric-coated pill, was studied
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