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Merck
CN

1677002

USP

醋酸曲安奈德

United States Pharmacopeia (USP) Reference Standard

别名:

9α-氟-11β,16α,17α,21-四羟基-1,4-孕甾二烯-3,20-二酮-16,17-丙酮化合物, 9α-氟-16α-羟基波尼松龙 16α,17α-丙酮化合物

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关于此项目

经验公式(希尔记法):
C24H31FO6
化学文摘社编号:
分子量:
434.50
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI key

YNDXUCZADRHECN-JNQJZLCISA-N

grade

pharmaceutical primary standard

API family

triamcinolone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... NR3C1(2908)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone acetonide USP reference standard intended for use in specified quality tests and assays.

Also used to prepare system suitability, standard, and standard stock solution for assay, impurity analysis, and performance tests according to the given below monographs of United States Pharmacopeia (USP):
  • Triamcinolone Hexacetonide
  • Triamcinolone Acetonide Injectable Suspension
  • Triamcinolone Acetonide Nasal Spray

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Triamcinolone Acetonide Nasal Spray
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5) (2021)
Triamcinolone Acetonide Injectable Suspension
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(3), 4490-4490 (2020)
Triamcinolone Hexacetonide
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 36(5), 4492-4492 (2020)
E M Becerra et al.
Current drug targets, 12(2), 149-172 (2010-10-05)
Triamcinolone acetonide (TA) is one of the first pharmacologic compounds evaluated for the treatment of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). The most important effects of TA consist in the stabilisation of the blood-retinal barrier and the
Mazen Abu-Mugheisib et al.
Current pharmaceutical design, 18(29), 4564-4569 (2012-05-23)
Multiple sclerosis (MS) as a chronic disease presents a vast variability of neurological symptoms. Spasticity is one of the most common symptoms. The principle indication to treat spasticity is disability or handicap of capabilities. All pharmacological methods are attributed to

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