900603
(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
≥95%
Synonym(s):
Amino (PEG)2 benzophenone alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C20H21NO4
CAS Number:
Molecular Weight:
339.39
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Assay:
≥95%
Form:
powder or crystals
InChI key
KXFOOVXWBVYUIH-UHFFFAOYSA-N
SMILES string
NCCOCCOc1ccc(cc1)C(=O)c2ccc(cc2)OCC#C
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry
storage temp.
−20°C
Quality Level
Related Categories
Application
(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its PEGylated amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
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