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文件

安全信息

安全和法规

M1750000

甲基强的松龙

Name: 甲基强的松龙
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

6α-甲基泼尼松龙, 11β,17α,21-三羟基-6α-甲基-1,4-孕甾二烯-3,20-二酮, 6α-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮, 甲基强的松龙, 甲基泼尼松龙

经验公式（希尔记法）:

C₂₂H₃₀O₅

CAS号:

83-43-2

分子量:

374.47

Beilstein:

2340300

MDL编号:

MFCD00010591

PubChem化学物质编号:

329817706

NACRES:

NA.24

等级

pharmaceutical primary standard

API family

methylprednisolone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

格式

neat

运输

wet ice

SMILES string

[H][C@@]12C[C@H](C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1

InChI key

VHRSUDSXCMQTMA-PJHHCJLFSA-N

Gene Information

human ... NR3C1(2908)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Methylprednisolone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Danger

危险声明

H360FD - H373

预防措施声明

P202 - P260 - P280 - P308 + P313 - P405 - P501

危险分类

Repr. 1B - STOT RE 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

法规信息

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示例

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货号

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Methylprednisolone in neonatal cardiac surgery: reduced inflammation without improved clinical outcome.

Juho Keski-Nisula et al.

The Annals of thoracic surgery, 95(6), 2126-2132 (2013-04-23)

Corticosteroids are widely used in pediatric open-heart surgery to reduce systemic inflammatory response and to mediate possible cardioprotective effects. However, the optimal dosing of corticosteroids is unknown and their administration varies considerably between different institutions. Forty neonates undergoing open-heart surgery

Diagnosis of Guillain-Barré syndrome and validation of Brighton criteria.

Christiaan Fokke et al.

Brain : a journal of neurology, 137(Pt 1), 33-43 (2013-10-29)

Guillain-Barré syndrome is an acute polyradiculoneuropathy with a variable clinical presentation. Accurate diagnostic criteria are essential for patient care and research, including clinical trials and vaccine safety studies. Several diagnostic criteria for Guillain-Barré syndrome have been proposed, including the recent

Spinal and paraspinal infections associated with contaminated methylprednisolone acetate injections - Michigan, 2012-2013.

MMWR. Morbidity and mortality weekly report, 62(19), 377-381 (2013-05-17)

As of May 6, 2013, Michigan had reported 167 (52%) of the 320 paraspinal or spinal infections without meningitis associated with the 2012-2013 fungal meningitis outbreak nationally. Although the index patient had a laboratory-confirmed Aspergillus fumigatus infection, the fungus most

Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs.

Emilio Portaccio et al.

Journal of neurology, neurosurgery, and psychiatry, 85(8), 845-850 (2014-01-10)

To assess relapses, disability progression and the role of disease modifying drugs (DMDs) in the year after delivery in women with multiple sclerosis (MS). We prospectively followed-up pregnancies occurring between 2002 and 2008 in women with MS, recruited from 21

Rationale and design of the steroids in cardiac surgery trial.

Richard Whitlock et al.

American heart journal, 167(5), 660-665 (2014-04-29)

Steroids may improve outcomes in high-risk patients undergoing cardiac surgery with the use of cardiopulmonary bypass (CBP). There is a need\ for a large randomized controlled trial to clarify the effect of steroids in such patients. We plan to randomize

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文件

安全信息

甲基强的松龙

European Pharmacopoeia (EP) Reference Standard

属性

等级

API family

manufacturer/tradename

application(s)

格式

运输

SMILES string

InChI

InChI key

Gene Information

相关类别

说明

一般描述

应用

包装

其他说明

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安全信息

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警示用语：

危险声明

预防措施声明

危险分类

储存分类代码

WGK

法规信息

文件

分析证书(COA)

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