This white paper illustrates the importance of three-dimensional (3D) cell culture in the production of pluripotent stem cell (PSC)-derived models of embryo development and differentiation. It contains a general overview of embryoid bodies (EBs) and a comparison between the various

Advanced Cell Culture Technology for Generation of In Vivo-like Tissue Models

Sophisticated models are developing as 3D cell culture technology becomes established and accepted as a means of creating more physiologically relevant cell-based assays.

An ECM Mimetic Library for Engineering Surfaces to Direct Cell Surface Receptor Binding Specificity and Signaling

The extracellular (ECM) microenvironment, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions. For this reason, engineering the ECM microenvironment provides

3D Cell Culture with Corning Microplates

Take a deep dive into the world of 3D cell culture courtesy of Corning and understand why the Corning® spheroid microplate can be an asset in the evolution of 3D cell culture.

MaxGel™ ECM Hydrogel: An In Vitro Human Cell Derived Basement Membrane Extract for 3D Cell Culture Applications

Human cell derived basement membrane extract (BME) hydrogel for 3D cell culture of primary cell, stem cell and xenograph cancer models.

dECM hydrogels 3D culture

Comparison of decellularized extracellular matrix (dECM) hydrogels to Matrigel® matrices for predictive 3D cell culture models

Photocrosslinkable Hydrogels for 3D Cell Culture and Tissue Engineering

Methacrylated collagen, hyaluronic acid, and gelatin (GelMA) hydrogels can be crosslinked with light and photoinitiators (Irgacure/LAP/Ruthenium), used as 3D cell culture scaffolds and bioinks for bioprinting.

Hydrogels for 3D Cell Culture

Hydrogela are the most widely used systems for 3D cell culture. Learn more about this technology (what are hydrogels? How to chose?)

3D Organoid Culture: New In Vitro Models of Development and Disease

Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.

TrueGel3D™ Hydrogel for 3D Cell Culture

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

Lung Cancer Organoid Biobank

Explore our cryopreserved human lung organoid biobank from NSCLC tumor biopsies for lung cancer, SARS-CoV2, COPD and pulmonary disease research. Lung organoid 3D cell culture protocol available.

Blood Brain Barrier Antibody Penetration Assay using Millicell® Microwell Plates

Discover a high throughput assay using organoids and Millicell® Microwell plates. Our novel blood brain barrier model allows direct cell-to-cell interactions, closely modeling the in vivo properties.

Millicell^® Ultra-Low Attachment Plates Spheroid Formation Performance Comparison

Learn about the similarities and differences in spheroid formation, roundness, and circularity between Millicell® ultra-low attachment plates and other ULA plates.

Millicell^® Ultra-Low Attachment (ULA) Plate FAQs

Learn how to grow spheroid cultures in ULA plates, the common applications and benefits of ULA plates for 3D cell culture, Millicell® ULA plate dimensions, plate handling, troubleshooting, and more.

HyStem™ Hyaluronic Acid Based Hydrogels for 3D Cell Culture Applications

Hystem 3D hydrogels are based on hyaluronic acid, a major component of the extracellular matrix. 3D cell culture can be done using Hystem hydrogels.

Cell Migration and Invasion Assay Guidance using Millicell^® Cell Culture Inserts

How to set up cell migration assays using cell culture inserts.

5 Reasons Cancer Researchers Adopt 3D Cell Culture: A Review of Recent Literature

Numerous cancer model systems are available to investigate disease mechanisms and to screen therapies. While all of the models have contributed critical information about cancer biology.

Attachment Factors for Three-dimensional Cell Culture

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

Extracellular Matrix Proteins and Tools for Cell Culture Optimization

Extracellular matrix proteins such as laminin, collagen, and fibronectin can be used as cell attachment substrates in cell culture.

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