跳转至内容
Merck
CN
  • Occurrence and Comparative Toxicity of Haloacetaldehyde Disinfection Byproducts in Drinking Water.

Occurrence and Comparative Toxicity of Haloacetaldehyde Disinfection Byproducts in Drinking Water.

Environmental science & technology (2015-05-06)
Clara H Jeong, Cristina Postigo, Susan D Richardson, Jane Ellen Simmons, Susana Y Kimura, Benito J Mariñas, Damia Barcelo, Pei Liang, Elizabeth D Wagner, Michael J Plewa
摘要

The introduction of drinking water disinfection greatly reduced waterborne diseases. However, the reaction between disinfectants and natural organic matter in the source water leads to an unintended consequence, the formation of drinking water disinfection byproducts (DBPs). The haloacetaldehydes (HALs) are the third largest group by weight of identified DBPs in drinking water. The primary objective of this study was to analyze the occurrence and comparative toxicity of the emerging HAL DBPs. A new HAL DBP, iodoacetaldehyde (IAL) was identified. This study provided the first systematic, quantitative comparison of HAL toxicity in Chinese hamster ovary cells. The rank order of HAL cytotoxicity is tribromoacetaldehyde (TBAL) ≈ chloroacetaldehyde (CAL) > dibromoacetaldehyde (DBAL) ≈ bromochloroacetaldehyde (BCAL) ≈ dibromochloroacetaldehyde (DBCAL) > IAL > bromoacetaldehyde (BAL) ≈ bromodichloroacetaldehyde (BDCAL) > dichloroacetaldehyde (DCAL) > trichloroacetaldehyde (TCAL). The HALs were highly cytotoxic compared to other DBP chemical classes. The rank order of HAL genotoxicity is DBAL > CAL ≈ DBCAL > TBAL ≈ BAL > BDCAL>BCAL ≈ DCAL>IAL. TCAL was not genotoxic. Because of their toxicity and abundance, further research is needed to investigate their mode of action to protect the public health and the environment.

材料
Product Number
品牌
产品描述

Sigma-Aldrich
甲醇, ACS reagent, ≥99.8%
Sigma-Aldrich
乙酸乙酯, ACS reagent, ≥99.5%
Sigma-Aldrich
乙腈, ACS reagent, ≥99.5%
Sigma-Aldrich
正己烷, ReagentPlus®, ≥99%
Sigma-Aldrich
乙腈, anhydrous, 99.8%
Sigma-Aldrich
丁基甲基醚, ACS reagent, ≥99.0%
Sigma-Aldrich
甲醇, anhydrous, 99.8%
Sigma-Aldrich
正己烷, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99% (GC)
Sigma-Aldrich
甲醇, Laboratory Reagent, ≥99.6%
Sigma-Aldrich
甲醇, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8% (GC)
Sigma-Aldrich
甲醇, ACS spectrophotometric grade, ≥99.9%
Sigma-Aldrich
正己烷, Laboratory Reagent, ≥95%
Sigma-Aldrich
甲醇, ACS reagent, ≥99.8%
Sigma-Aldrich
乙酸乙酯, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)
Sigma-Aldrich
乙酸乙酯, anhydrous, 99.8%
Sigma-Aldrich
丁基甲基醚, reagent grade, ≥98%
Sigma-Aldrich
正己烷, anhydrous, 95%
Sigma-Aldrich
丁基甲基醚, anhydrous, 99.8%
Sigma-Aldrich
甲醇, BioReagent, ≥99.93%
Sigma-Aldrich
丁基甲基醚, puriss. p.a., ≥99.5% (GC)
Sigma-Aldrich
乙腈, biotech. grade, ≥99.93%
Sigma-Aldrich
乙腈, electronic grade, 99.999% trace metals basis
Sigma-Aldrich
甲醇, ACS reagent, ≥99.8%
Sigma-Aldrich
乙腈, suitable for DNA synthesis, ≥99.9% (GC)
Sigma-Aldrich
乙酸乙酯, ≥99%, FCC, FG
Sigma-Aldrich
乙酸乙酯, ACS reagent, ≥99.5%
Sigma-Aldrich
乙酸乙酯, puriss., meets analytical specification of Ph. Eur., BP, NF, ≥99.5% (GC)
Sigma-Aldrich
乙腈, ReagentPlus®, 99%
Sigma-Aldrich
甲醇, puriss., meets analytical specification of Ph Eur, ≥99.7% (GC)
Sigma-Aldrich
乙酸乙酯, natural, ≥99%, FCC, FG