BACE1
beta-site APP-cleaving enzyme 1
别名:
ASP2, BACE, HSPC104
物种:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Horse BACE1 (100071137), naked mole-rat Bace1 (101701890), sheep BACE1 (101119667), dog BACE1 (489390), cow BACE1 (614333), chicken BACE1 (419768), Zebrafish bace1 (403005) ...展开
UniProtKB ID:
基因ID:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
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