Merck
CN
  • A new quantitative method to determine the uptake of SPIONs in animal tissue and its application to determine the quantity of nanoparticles in the liver and lung of Balb-c mice exposed to the SPIONs.

A new quantitative method to determine the uptake of SPIONs in animal tissue and its application to determine the quantity of nanoparticles in the liver and lung of Balb-c mice exposed to the SPIONs.

Journal of biomedical nanotechnology (2013-05-01)
R D Zysler, E Lima, M Vasquez Mansilla, H E Troiani, M L Mojica Pisciotti, P Gurman, A Lamagna, L Colombo
PMID23627077
摘要

We propose a new method for determining the quantity of superparamagnetic iron oxide nanoparticles (Fe3O4, SPIONs) embedded in animal tissue using magnetization measurements. With this method, the smallest detectable quantity of magnetite nanoparticles in a tissue sample is -1 microg. We showed that this method has proved being efficient. In this study, we focused in determining the quantity of SPION confined in lung and liver tissue of mice injected with -13 nm magnetite superparamagnetic nanoparticles. Furthermore, the method allowed us to detect the magnetite nanoparticles present in animal tissues without letting the natural iron ions present in the tissue or blood interfere with the measurements.

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31392
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31390
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葡聚糖 来源于明串珠菌 属, Mr ~70,000
D8802
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葡聚糖 溶液 来源于肠系膜明串珠菌, 20 % (w/w) (Autoclaved)
31389
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葡聚糖 来源于明串珠菌 属, Mr ~40,000
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31388
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D4876
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葡聚糖 来源于肠系膜明串珠菌, average mol wt 150,000
00894
Supelco
右旋糖酐, analytical standard, for GPC, 270,000
00893
Supelco
右旋糖酐, analytical standard, for GPC, 150,000
00271
Supelco
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31430
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00268
Supelco
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Supelco
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00270
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31398
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