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Merck
CN

DRD4

dopamine receptor D4

别名:
D4DR
物种:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)
UniProtKB ID:
P21917, B0M0J7, Q7Z7Q5, Q8NGM5
基因ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

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Small Molecule - Agonist

Product Number
说明
物种
P233
PD 168,077 maleate salt, powder,
物种
human
A1237
普拉克索 二盐酸盐, >98% (HPLC), powder,
物种
human
PHR1633
盐酸罗匹尼罗, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1605205
罗匹尼罗 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
Y0001773
罗匹尼罗 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

Product Number
说明
物种
L131
L-745,870 hydrochloride, ,
物种
human
U115
U-101958 maleate salt, solid,
物种
human
L135
L-741,626, ≥98% (HPLC),
物种
human
C-904
氯丙嗪盐酸盐标准液 盐酸盐, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
1125006
氯丙嗪 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

Product Number
说明
物种反应性
应用
MABN125
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
物种反应性
human, mouse, rat
应用
immunocytochemistry
western blot
AB1787P
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
物种反应性
mouse
应用
ELISA
western blot
HPA062682
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
324405
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
物种反应性
human, rat
应用

Small Molecule - Inhibitor

Product Number
说明
物种
D052
GBR 12909 二盐酸盐, solid, ≥98% (HPLC),
物种
human
A-123
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
物种
human
1031401
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
物种
human
PHR1841
阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
A129
Amoxapine, ,
物种
human

Small Molecule - Metabolite

Product Number
说明
物种
H3132
3-羟基-4-甲氧基苯乙胺 盐酸盐, ,
物种
human
M4251
3-甲氧基酪胺 盐酸盐, ≥95.5%, crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
说明
物种
B9308
BP897, >98% (HPLC), solid,
物种
human, rat
H1512
氟哌啶醇, powder,
物种
human, rat
C6305
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

Product Number
说明
物种
D9628
左旋多巴, ≥98% (TLC),
物种
mouse, human, rat
D9503
3,4-二羟基- DL- 苯丙氨酸, ,
物种
mouse, human, rat

Proteins

Product Number
说明
物种
AG222
Dopamine D4 Receptor, control peptide for AB1789/AB1789P, ,
物种
rat

esiRNA

Product Number
说明
物种
EMU028911
MISSION® esiRNA, targeting mouse Drd4,
物种
mouse