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Characterization of TolC efflux pump proteins from Pasteurella multocida.

Characterization of TolC efflux pump proteins from Pasteurella multocida.

Antimicrobial agents and chemotherapy (2008-08-30)

Tamas Hatfaludi, Keith Al-Hasani, Michelle Dunstone, John Boyce, Ben Adler

摘要

Two TolC homologs, PM0527 and PM1980, were identified for Pasteurella multocida. A pm0527 mutant displayed increased susceptibility to a range of chemicals, including rifampin (512-fold) and acridine orange (128-fold). A pm1980 mutant showed increased susceptibility to rifampin, ceftazidime, and vancomycin.

材料

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